Endocrine Abstracts

Diabetes, one of the most commonly seen metabolic disorders, is affecting a major area of population in many developing as well as most of the developed countries and is becoming an alarming concern for the rising cost of the healthcare system. Latent Autoimmune Diabetes in Adults (LADA) is a form of diabetes which is less recognized and under diagnosed type of diabetes which appears to have characteristics of both type 1 (autoimmune in nature) and type 2 diabetes (adult age a...

The aim of study was to recurrently follow quality of life in type 1 diabetes patients after multiple educations and counseling. Ninty six patients of the age group of “between” 10 to 25 were initially examined in 2004 and Eighty eight patients of them were reexamined in 2006 after multiple counseling with diabetologist and trained diabetes educator at dia care, Ahmedabad, Gujarat, India. Quality of life was defined as perceived well being and life satisfaction, glob...

The study was aimed to compare the outcome of pregnancies in women with type 1 diabetes treated with continuous subcutaneous insulin infusion pump (CSII) or multiple insulin injections (MDI). Total 14 patients were treated with insulin pump and 20 patients were treated with multiple injections; were mainly investigated for HbA1c, incidence of hypoglycemia, fetal outcome, rates of pregnancy induced hypertension and cesarean section. HbA1c with insulin pump was significantly bet...

Introduction: The MC4R pathway is the principal regulator of mammalian energy balance through its modulation of energy intake and energy expenditure. Variants in genes associated with the MC4R pathway can result in rare genetic diseases of obesity. Clinical data in patients with certain genetic defects in the MC4R pathway indicate that setmelanotide, an MC4R agonist, may effectively reduce weight and hunger in scientifically rationalized obese subpopulations in which MC4R-path...

Introduction: Refined carbohydrates which substitute the staple diet in most cultures may exaggerate postprandial responses in term of insulin and free fatty acid levels. These changes may herald the onset of metabolic syndrome and diabetes among those at high risk of these diseases.Objectives: To determine the postprandial insulin and free fatty acids levels in healthy subjects after the consumption of two different breakfast meals, Mediterranean-like v...